How to take VITRAKVI®

Dosing guidance

  • Take VITRAKVI exactly as your healthcare provider tells you and report any side effects you may experience

  • Your healthcare provider may stop treatment or change your dose of VITRAKVI if you have side effects. Do not change your dose or stop taking VITRAKVI unless your healthcare provider tells you

  • If you have any questions, talk to your healthcare provider or pharmacist

Additional VITRAKVI dosing considerations


VITRAKVI is usually taken by mouth 2 times a day. Take VITRAKVI with or without food

  • If you vomit after taking a dose of VITRAKVI, wait and take the next dose at your scheduled time

  • If you miss a dose of VITRAKVI, take it as soon as you remember. If your next scheduled dose is due within 6 hours, skip the missed dose and take your next dose at your regular time

VITRAKVI comes in capsules and a liquid formulation

VITRAKVI® (larotrectinib) Capsule Icon
  • The liquid formulation can be given to children under 18 years old or adults

  • Swallow VITRAKVI capsules whole with water. Do not chew or crush the capsules

If your healthcare provider prescribes VITRAKVI liquid formulation

  • Your healthcare provider will provide you with the VITRAKVI liquid formulation and oral syringes or send you to a pharmacy that can provide you with VITRAKVI liquid formulation and oral syringes

  • Your healthcare provider should show you how to correctly measure and give a dose of VITRAKVI liquid formulation

  • See the detailed Instructions for Use that come with VITRAKVI liquid formulation for information about the correct way to measure and give a dose of VITRAKVI liquid formulation

Keep VITRAKVI liquid formulation in the refrigerator. Do not freeze

VITRAKVI® (larotrectinib) Liquid Form Icon
  • Throw away any unused VITRAKVI liquid formulation after 90 days of first opening the bottle

  • If you take too much VITRAKVI, call your healthcare provider or go to the nearest hospital emergency room right away