204 out of 339 patients had a response to treatment
A responsea means that the cancer reduced in size and/or completely disappeared. Responses were analyzed across 3 clinical trials in 339 adults and children with TRK fusion cancer.
How long patients responded to treatment at time of analysis
- In patients who had their tumors disappear or shrink, responses lasted for a medianc of 43.3 months, with a range of 0.0+ months and 73.7+ monthsd
- 64% of patients had a response that lasted more than 12 months
- 45% of patients had a response that lasted more than 24 months
- The medianc time it took patients to respond to treatment was 2.22 monthse
a A response is a sum of partial response and complete response. Partial response is defined as a reduction in size of target tumors by 30% or more and complete response is defined as complete disappearance of all target tumors.
b 5% were patients who had a partial response and were able to have surgery to be disease free when the study data was analyzed.
c The median is the middle number in a group of numbers.
d The duration of response is how long the response to treatment lasted.
e Range: 0.89 month to 35.84 months.