41 out of 55 patients had a response to treatment
A response* means that the cancer reduced in size and/or completely disappeared. Responses were analyzed across 3 clinical trials in 55 adults and children with TRK fusion cancer.
How long patients responded to treatment at time of analysis
In patients who had their tumors disappear or shrink, responses lasted for a median‡ of 32.9 months, with a range of 1.6+ months and 50+ months§
63% of patients had a response that lasted more than 12 months
49% of patients had a response that lasted more than 24 months
The median‡ time it took patients to respond to treatment was less than 2 months‖
*A response is a sum of partial response and complete response. Partial response is defined as a reduction in size of target tumors by 30% or more and complete response is defined as complete disappearance of all target tumors.
†5% were patients who had a partial response and were able to have surgery to be disease free when the study data was analyzed.
‡The median is the middle number in a group of numbers.
§The duration of response is how long the response to treatment lasted.
‖Range: 0.95 month to 14.55 months.